Automating NGS prep

NGS

Automating NGS prep

Hero ngs

Automating next-generation sequencing (NGS) workflows brings immediate benefits to the lab by increasing consistency, improving reproducibility, and significantly extending walk-away time. This leads to a more robust and scalable workflow that supports high-throughput sequencing demands while freeing up staff to focus on analysis and experiment design rather than repetitive sample prep tasks. 

3 reasons to automate NGS prep

Eliminate variability from NGS prep

Control every step of the process—from bead mixing to thermal cycling

Maximize throughput and walkaway time

Coordinate all devices and allow for unattended operation 

Ensure complete sample traceability

Integrate with LIMS, enabling bi-directional communication and results reporting 

Typical NGS prep workflow

Typical NGS prep workcells

No matter your goals or throughput needs, we can design and implement a solution to automate your NGS prep workflow.  

Small workcell

Small workcell
Labware/Throughput Capacity: 75 MTP Plates in Hotels, 135 MTP Plates in Stacks

Medium workcell

Medium workcell
Labware/Throughput Capacity: 225 MTP Plates in Stackers, 125 MTP Plates in Hotels

Large workcell

Large workcell
Capacity: 3,080 Microtiter Plates, 36,000 Matrix Tubes

Best use cases for bringing in automation

When uniformity is critical

Automation delivers workflow consistency and sample traceability by reducing manual touchpoints 

When working over night or on weekends is a regular requirement

Automation unlocks walkaway time for staff so that runs can continue every single hour of the week 

High-throughput sequencing and regulated environments

Automation delivers robust, scalable, and audit-ready processes 

What to watch out for

Sample tracking and release steps may still require manual review if not integrated with a LIMS 

Informatics infrastructure must manage the volume of metadata and intermediate QC points generated by automated prep

Increased usage of labware and tips can require operational changes

Complex library prep protocols may need to be adapted for automation compatability

Accelerate your science with Biosero today